Glutathione, a tripeptide that serves as a fundamental antioxidant in both eukaryotic and prokaryotic cells, is at the forefront of research in metabolic engineering. Its pivotal role in maintaining ...

Abstract: The use of microbial systems for synthetic purposes holds significant promise in the realm of green manufacturing. However, in order to fully unleash the potential of these systems, it is ...

A research team has developed an enzyme that robustly and efficiently reduces formate to formaldehyde. This synthetic ...

Plants have developed an extraordinary ability to synthesize a diverse array of secondary metabolites. These compounds are ...

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study from St. Jude Children's Research Hospital, published in Cell, ...

Dietary restriction reshapes CD8+ T cell metabolism by increasing ketone body–driven acetyl-CoA production, preventing ...

In recent years, the complex ecosystem surrounding cancer cells, known as the tumor microenvironment (TME), has become a ...

A growing body of work suggests that cell metabolism — the chemical reactions that provide energy and building materials — plays a vital, overlooked role in the first steps of life. Each of us starts ...

A growing body of evidence implicates cellular senescence—when cells age and permanently stop dividing—as an important contributor to metabolic dysfunction that can lead to obesity, type 2 diabetes, ...

Researchers find high-fat diets set off metabolic dysfunction in cells, leading to weight gain, but these effects can be reversed by treatment with an antioxidant. Consuming a high-fat diet can lead ...