Two years after this, Sakaguchi was able to link these discoveries. He proved that the Foxp3 gene governs the development of ...

When the immune system overreacts and starts attacking the body, the only option may be to shut the entire system down and risk developing infections or cancer. Immune cells that are designed to ...

Researchers at the University of Arizona have uncovered a previously unknown population of circulating immune cells that play a critical role in fibrosis, the buildup of scar tissue that can lead to ...

Borrowing a cancer cell’s disguise, scientists shielded insulin-producing cells from attack by the immune system, a breakthrough that could pave the way for targeted type 1 diabetes treatments without ...

A new study has revealed that a special group of cells in the intestines tamp down the immune responses caused by exposure to food proteins. Called 'tolerogenic dendritic cells,' these cells enable ...

A rare cell type in the lungs is essential to survival from the COVID-19 virus, a new study shows. Experiments in mice infected with the SARS-CoV-2 virus revealed that the immune cell class in ...

Why do certain immune cells remain permanently active in allergic asthma—even in an environment that should actually damage ...

One challenge of using cell therapy to treat type 1 diabetes is that this approach requires chronic suppression of the immune system to prevent rejection of donor cells. A Vertex Pharmaceuticals ...

A combination blood stem cell and pancreatic islet cell transplant from an immunologically mismatched donor completely prevented or cured Type 1 diabetes in mice in a study by Stanford Medicine ...