In the limited space of the nucleus, most of the genome is tightly folded, leaving accessible only the parts that need to be transcribed. There is “huge interest” in determining which elements of the ...

The Saint Louis University Genomics and Bioinformatics Core Facility provides state-of-the-art single-cell genomics and integrative bioinformatics services to both internal and external researchers.

Understanding a drug’s mechanism of action (MOA) can greatly increase the likelihood of successful clinical trials by identifying biomarkers of patient response and providing a rationale for ...

A major new review article led by researchers from the School of Mathematics at Harbin Institute of Technology has just been published in Quantitative Biology, offering a comprehensive comparison of ...

Despite spanning about three billion base pairs, the human genome is wrapped up tight in a highly organized fashion in the nucleus. This coordinated structure, in part, enables the cell to regulate ...