The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...
Scripps Research scientists have discovered how some tumors endure DNA damage, revealing a potential new way to target them. The DNA inside our cells is constantly exposed to damage, and one of the ...
By the way, GSK, realizing its potential in the MSI-H/dMMR market, is actively developing it for the treatment of colon ...
Mycosis fungoides, the most prevalent CTCL subtype, accounts for the majority of cases. Although early-stage disease has a five-year survival rate of roughly 88%, it is a chronic cancer with ...
Memorial Sloan Kettering Cancer Center researchers continued to make strides against cancer in 2025. Learn about some of ...
Cutaneous T-cell lymphoma (CTCL) is a rare subtype of non-Hodgkin’s lymphoma that disproportionately affects older adults. SNGX’s confirmatory FLASH2 study represents the final major step toward ...
Ideaya Biosciences receives US FDA clearance to initiate phase 1 trial to evaluate IDE034, a potential first-in-class bispecific B7H3/PTK7 TOP1 ADC targeting multiple solid tumour types ...
Morning Overview on MSN
Early trials hint a ‘functional cure’ for HIV is near
For the first time since HIV was identified, early human trials are starting to show what long‑imagined “drug‑free control” ...
YouTube has released its annual “Global Culture & Trends Report” for 2025, analyzing the platform’s most-subscribed creators, ...
D microscopy shows that the giant bacterium Thiovulum imperiosus squeezes its DNA into peripheral pouches, not a central mass ...
8don MSN
CDT1 overexpression suppresses DNA replication and triggers DNA damage linked to cancer, finds study
A research group has demonstrated that overexpression of Cdc10-dependent transcript 1 (CDT1), a key regulator of DNA ...
News-Medical.Net on MSN
New method reveals how human cells initiate DNA replication
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...
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