A study on worms led by researchers from Vanderbilt University School of Medicine in the US has uncovered a previously unknown adaptation to aging that actively remodels one of the largest and most ...

By Pooja Toshniwal Paharia Preclinical studies increasingly place circular RNAs at the intersection of thermogenic programming and organelle stress control, raising the possibility that these stable ...

Unique metabolic architectureCells have to break down sugar to produce energy. In most organisms, this process of glycolysis takes place in the ...

This study reports an important and novel finding that TENT5A, an enzyme involved in fine-tuning poly(A) tail length on selected mRNAs, is required for proper enamel mineralization in mice. The ...

Microplastics in the air are infiltrating human lungs, triggering oxidative stress, inflammation and cellular damage that may contribute to a range of serious respiratory diseases, a comprehensive new ...

A protein’s life is anything but simple. Discover how transcription, translation, folding, modification, and degradation work together to preserve proteome integrity.

Innovations in imaging and genetic engineering are coming together to probe the biophysics of cytoplasm inside living animals.

Improvements in public health have allowed humankind to survive to older ages than ever before, but, for many people, these added golden years are not spent in good health. Aging is a natural part of ...

As we age, our cells don’t just wear down—they reorganize. Researchers found that cells actively remodel a key structure called the endoplasmic reticulum, reducing protein-producing regions while ...

Yeast, worms, and mice remodel their endoplasmic reticulum early in the aging process. The protective shift offers potential targets to extend healthy lifespan.