Feb 8, 2025 · When mitophagy is induced, Atg32 binds to Atg11, an adaptor protein for selective autophagy. Atg32 is a transmembrane receptor that directs autophagosome formation to …

Nomenclature history: The standard name of YIL146C was changed from ECM37 (ExtraCellular Mutant) to ATG32 (AuTophaGy related) based on consensus of the YIL146C research …

Jul 21, 2009 · We designated this autophagy-related (ATG) gene as ATG32. The Atg32 protein localizes on mitochondria. Following the induction of mitophagy, Atg32 binds Atg11, an …

We designated this autoph-agy-related (ATG) gene as ATG32. The Atg32 protein localizes on mitochondria. Following the induction of mitophagy, Atg32 binds Atg11, an adaptor protein for …

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Jul 27, 2017 · In Saccharomyces cerevisiae, mitophagy is dependent on the autophagy receptor, Atg32, an outer mitochondrial membrane protein. Once activated, Atg32 recruits the …

Jul 6, 2015 · Our findings offer insights into mitochondrial quality control in mammalian cells. Atg32 is required for mitophagy in yeast, however, a mammalian homologue of this protein …

Aug 26, 2024 · Most autophagy-related (ATG) genes have been identified and characterized through studies using the budding yeast Saccharomyces cerevisiae.

In budding yeast, autophagy-related protein 32 (Atg32) is inserted into the outer membrane of mitochondria with its N- and C-terminal domains exposed to the cytosol and mitochondrial …

The modified Atg32 is targeted to the vacuole where it becomes sta-bilized when vacuolar proteases are deficient. Interestingly, we find that this degradation pathway differs from the …